POINT: improving post-COVID-19 care

Overview

POINT is an innovative research project funded by the European Union with a mission to mitigate the long-term health risks associated with COVID-19. By harnessing advanced biomarkers and a virtual twin model for personalized care, we aim to bridge the gap between scientific discoveries and their practical application in clinical settings. Our goal is to gain a comprehensive understanding of the post-acute phase of COVID-19 and equip healthcare professionals with the necessary tools and guidelines to effectively manage patients.

Objectives

Exploring the mechanistic link and risk factors

POINT will delve into the relationship between the post-acute phase of COVID-19 and the emergence of non-communicable diseases (NCDs), with a focus on the pulmonary, cardiovascular, and renal systems. Through the analysis of extensive cohort studies and biobanks, we aim to shed light on the clinical, biological, and socioeconomic factors that contribute to this heightened risk.

Developing biomarkers and predictive tools

POINT will identify and validate biomarkers as early indicators of health complications in COVID-19 survivors. We will develop a virtual twin model to replicate tissue function post-infection, facilitating timely assessments and preventive actions. These tools will help to forecast the influence of comorbidities and medication, and to track disease progression and the underlying causes.

Establishing standardised guidelines

POINT will create guidelines for healthcare professionals to optimise risk management and preventive care strategies. These guidelines will be adapted to European and international standards, with an emphasis on the inclusion of vulnerable populations. Feasibility studies and continuous adherence assessments will ensure that the guidelines are fit for purpose.

Impact

POINT has the potential to revolutionise our approach to  post-COVID-19 health issues. This research project offers a promising opportunity for healthcare professionals and authorities in Europe to improve how they manage  these challenges.

Through POINT, we will:

  • Optimise the management of patients and alleviate the societal burden of non-communicable diseases
  • Lead to early identification and effective treatment of patients at risk, ensuring a higher quality of life
  • Promote greater patient inclusion and adherence to the guidelines developed
  • Offer insights applicable to other infectious diseases and non-communicable diseases
  • Empower citizens and patients with health literacy, encouraging them to seek advice and reducing the risk of non-communicable diseases after COVID-19
  • Ensure that millions of patients receive the attention and treatment they need to prevent long-term health complications

Project Team

The project is coordinated by the University of Copenhagen (UCPH) and run by an interdisciplinary team of ten organisations across Europe. This team draws on the expertise of clinical, molecular, behavioural scientists and computer scientists.